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Generic Viagra (sildenafil) is an erectogenic pill with dozens of patient-years backing up its unprecedented safety and efficacy in the treatment of erectile disability. Taken on demand, Generic Viagra restores the sexual function for the period of 4 hours, dramatically increasing penetrative hardness of the penis and decreasing the refractory period after every ejaculation.

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Viagra is a great drug that many men cannot help but applaud. However, with its miracle power to give the flagging sex life a second wind, Viagra is equally good to reduce an inspired man to poverty. Yes, we are serious. The cost of branded Viagra is nearly $20 per a 50 mg pill, and if you got hooked on having sex, at least, three times a week, you will pay too dear for your whistle.

But there is a solution to every problem.

Can-Generic-Viagra-Really-Mend-Poor-Sexual-StaminaConsidering the acute need of common patients for an affordable, yet effective and safe, erectile dysfunction remedy, pharmaceutical makers started producing analogs to Viagra with the same active ingredient – Sildenafil Citrate. Generic Viagra is equal to original in most respects: mode of action, efficacy, safety as well as contraindications. Major differences root from the visual appearance of the generic version, its name, and, ultimately, price.

Though Generic Viagra is 100% bio-equivalent to the genuine drug, there are hordes of people who meet analog medicine with harsh skepticism. They doubt whether Generic Viagra can really cure impotence as effectively as the primary medication. Mexican Pharmacy is to hunt down this question. But first, let’s find out how generic Viagra counterparts gained the right of existence…

Historical Notes

Original Viagra was patented by the Pfizer Company in remote 1998. The drug contained the key agent called Sildenafil and was the first prescription drug on the pharmaceutical market for the management of erectile dysfunction. The patent lasted up to 2013 and until that year, only Pfizer had the exclusive rights to produce Viagra.

But the patent ran out in 2013, which let other pharmacies produce their own versions of this drug, however, without the right to call their products Viagra because it is the trademark of Pfizer – the sole owner of this name. Manufacturers have to market their Generic Viagra as Sildenafil. Apart from retaining the Viagra name, Pfizer also preserved the exclusive rights on the physical appearance of the medicine – the blue diamond-shaped hard tablet. Consequently, other drug makers cannot use the same appearance for their Generic Viagra products. For this reason, Generic Viagra is sold in many forms: coated white or rosy tablets, chewable capsules or even oral jelly.

Pharmaceutical manufacturers must comply with international standards imposed on the generic versions of Viagra. Such as, Generic Viagra must contain the same active ingredient and in the same amount and be produced under the same manufacturing conditions as genuine Viagra. The branded preparation is available in the strengths of 25 mg, 50 mg, and 100 mg. And this means that Generic Viagra is sold in the same dose denominations.

Is Generic Viagra Able To Treat Sexual Impotence?

To begin with, erectile dysfunction is not a disease, but a symptom of some other health problems. Consequently, Generic Viagra just reverses the symptom and does not cure the disease which evoked ED. Erectile dysfunction is a condition which might stem from different mental or physical illnesses including hypertension, cardiovascular disease, diabetes, obesity, pelvic surgery, dyslipidemia, endothelial dysfunction, multiple sclerosis, and hypogenitalism to name a few. To get completely rid of erectile dysfunction (the consequence), it is necessary to treat the underlying disease (the cause).

Before allowing original Viagra to hit the market, there were dozens of randomized, double-blind, placebo-controlled clinical experiments in different populations of men suffering from a sexual disability. And those studies demonstrated the efficacy and favorable safety profile of Sildenafil including in those patients whose ED was induced by one or several comorbid conditions such as diabetes mellitus. And you know that generic counterparts must feature the same effectiveness and safety as the pioneer drug, and Generic Viagra never fails to prove this true.

How does Generic Viagra Work?

It works in the same way as the genuine medicine. Sildenafil is a selective inhibitor of PDE type 5. The drug can enhance nitric oxide-mediated relaxation of smooth muscle in the cavernous bodies. Sildenafil blocks phosphodiesterase and promotes the increase of the intracellular levels of cyclic guanosine monophosphate (cGMP). Such a reaction triggers the amplification of the NO (nitric oxide)-cGMP signaling pathway, or, in plain words, expands the blood vessels inside a penis. Better blood flow makes the penis harder, and an erection eventually comes.

The onset of action is within 15 minutes, and the window to engage in sexual intercourse is kept for up to 12 hours after administration. If consumed with a fatty meal, Generic Viagra may take more time to start working, while small amounts of alcohol do not influence the absorption of the drug. The time to maximum concentration in plasma is about 1 hour, while the plasma half-life is up to 5 hours.

Generic Viagra is taken on demand, better one hour prior to an anticipated intimacy, and the dosing frequency should not exceed once in 24 hours. The recommended initial dose is 50 mg which can be either increased or reduced depending on a patient’s tolerability. Interestingly that Sildenafil does not work in the absence of sexual arousal – the prerequisite for nitric oxide releases in male corpus cavernosum. This indicates that Generic Viagra is not an aphrodisiac and is not able to evoke an erection in a man if he is not sexually excited.

Generic Viagra Safety

Just like its precursor, Generic Viagra has only one absolute contraindication: the concomitant use of nitrates or other heart medications. Still, there are some other pharmaceuticals which require adjustments of Sildenafil doses (should be discussed with a doctor, surely):

  • Carbamazepine,
  • Clarithromycin,
  • Erythromycin,
  • HIV protease inhibitors (ritonavir, saquinavir),
  • Itraconazole,
  • Ketoconazole,
  • Phenobarbital,
  • Phenytoin,
  • Rifampin.

Generic Viagra Questions Which Torture Most Patients

Generic-ViagraGot questions about Generic Viagra? Medicirc fields them all! Find answers to the most serious questions which might prevent you from buying Generic Viagra.

What adverse events may happen after consuming Generic Viagra?

The most common treatment-related reactions include headache, facial redness, dyspepsia, dizziness, nasal congestion, visual disturbances, and rapid heart rate. Uncommon or rare side-effects include pain in the back and limbs, tremor, gastrointestinal events, hypersensitivity reactions. Side-effects are dose-related and are not severe in nature. Sildenafil tolerance is individual and depends on pre-existing conditions.

Why does Generic Viagra cause visual disorders?

Visual issues like changed color perception or blurred vision may take place, too, after taking Sildenafil. It is associated with the drug’s ability to partly inhibit protein complex PDE6 which is abundant in the retina. Such reaction may occur during the peak concentration of Sildenafil in plasma, but, fortunately, it is temperate and fully reversible.

Can elderly patients safely take Generic Viagra?

Elderly men are at a high risk of developing erectile dysfunction. Sildenafil Citrate was thoroughly tested in terms of safety and effectiveness in adult men with ED, and it was proved that the oral drug is efficacious and well-tolerated in men over 60 and older.

Is Generic Viagra safe for patients with liver conditions?

Sildenafil has no effect on individuals with hepatic conditions. It is clinically established that Sildenafil had no effect on end-stage liver disease. Numerous studies on hepatic patients with ED show that Sildenafil does not cause any significant changes in splanchnic blood flow, oxygen intake and hepatic venous pressure gradient in men with cirrhosis. Severe liver diseases suggest consultations with a caring physician and corrections of Sildenafil doses.

How is Generic Viagra tolerated under kidney diseases?

Patients with renal conditions can usually take Sildenafil in the normal way provided their kidney function is not severely impaired. Many clinical trials have shown the efficacy of Sildenafil for the management of impotence in dialysis men and in renal transplant recipients, still, not without side-effects (facial redness, headaches, digestive disorder). However, to check the individual tolerance, it is better to start with a minimal dose of Sildenafil (25 mg) for patients with a compromised kidney function.

Is there any association between Generic Viagra and cardiovascular risk?

If you do not have underlying cardiovascular conditions, Generic Viagra is pretty safe. The drug is not dangerous for healthy hearts, but men with heart problems are at risk of developing strong after-effects if they take Sildenafil without thinking twice. The matter is that nitric oxide is released by all blood vessels, not just those in the sex organ. This means that all blood vessels can expand in response to Sildenafil inducing blood pressure decrease by 5-10 mmHg even in healthy men.

Organic nitrates are the medicines which expand blood vessels, too, by increasing the level of nitric oxide in them. For this reason, nitrates like nitroglycerin and Sildenafil are very bad mixers – when taken together, they pose a significant risk of a fatal outcome. Consequently, patients who have recently undergone a heart attack, stroke, congestive heart failure or unstable angina or who are currently struggling from hypertension and have to take heart medicine must take Sildenafil with extreme caution.

Product Disclaimer: The information presented in this article was published for informational purposes only and cannot be used to diagnose or treat medical conditions without a consultation with a medical professional. Mexicocityusa.org does not provide any medical services or consultations. This website is not liable for misuse of any information provided in this article. Always consult a doctor before using any information provided on this page.